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Vor Biopharma (VOR) investor relations material
Vor Biopharma Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Repositioned focus on telitacicept, advancing global Phase 3 trials in generalized myasthenia gravis (gMG) and primary Sjögren's disease (SjD).
First patient dosed in global Phase 3 trial for SjD; topline data for gMG expected in 1H 2027.
$75 million private placement completed to support clinical development.
Financial highlights
Pro-forma cash and investments of $530.2 million as of December 31, 2025, including proceeds from March 2026 private placement, expected to fund operations into early 2029.
R&D expenses for Q4 2025 were $19.2 million, down from $25.3 million in Q4 2024; full-year 2025 R&D expenses rose to $321.5 million from $93.3 million in 2024, mainly due to telitacicept license purchase.
G&A expenses for Q4 2025 were $16.8 million, up from $6.0 million in Q4 2024; full-year 2025 G&A expenses increased to $50.1 million from $27.9 million in 2024.
Net income for Q4 2025 was $1,722.8 million, compared to a $30.7 million net loss in Q4 2024, driven by a gain on change in fair value of liability-classified warrants.
Net loss for full-year 2025 was $696.0 million, compared to $116.9 million in 2024, mainly due to loss on warrant fair value and telitacicept license purchase.
Outlook and guidance
Topline data from the global Phase 3 gMG trial expected in the first half of 2027.
Cash runway projected into early 2029.
- Telitacicept delivers robust, durable efficacy and safety in major autoimmune diseases, enabling global expansion.VOR
Corporate presentation9 Mar 2026 - Telitacicept advances in late-stage trials for MG and Sjögren's, targeting major autoimmune markets.VOR
TD Cowen 46th Annual Health Care Conference2 Mar 2026 - Gene-edited stem cell transplants for AML show strong early results and pivotal trial progress.VOR
Oppenheimer 35th Annual Healthcare Life Sciences Conference 20253 Feb 2026 - 13.9M shares registered for resale after $150M private placement; no proceeds to the company.VOR
Registration Filing29 Jan 2026 - Trem-cel with Mylotarg yields rapid engraftment and promising RFS in high-risk AML.VOR
Study Update22 Jan 2026 - Telitacicept advances in global Phase 3 trials for MG and Sjögren's, backed by strong data and funding.VOR
44th Annual J.P. Morgan Healthcare Conference16 Jan 2026 - Promising AML trial results, phase III plans, and pipeline growth signal strong momentum.VOR
Stifel 2024 Healthcare Conference13 Jan 2026 - Trem-cel enables rapid engraftment, strong safety, and improved relapse-free survival in AML.VOR
Status Update11 Jan 2026 - Registering 125.7M shares post-private placement to fund AML therapy R&D; major investors join board.VOR
Registration Filing16 Dec 2025
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