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Precision BioSciences (DTIL) investor relations material

Precision BioSciences Registration Filing summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Registration Filing summary30 Dec, 2025

Company overview and business model

  • Clinical-stage gene editing company focused on in vivo therapies for genetic and infectious diseases using the proprietary ARCUS genome editing platform, which enables precise gene edits including insertion, excision, and elimination.

  • Lead programs include PBGENE-HBV, a first-in-human clinical trial for chronic Hepatitis B, and PBGENE-DMD, targeting Duchenne muscular dystrophy with an anticipated IND filing by end of 2025.

  • ARCUS platform's small size allows for delivery to a broad range of cells and tissues via viral and non-viral methods.

Financial performance and metrics

  • As of September 30, 2025, pro forma net tangible book value was $3.74 per share, increasing to $3.88 per share after the offering, with immediate dilution of $0.35 per share to new investors.

  • Net tangible book value as of September 30, 2025, was $15.6 million, or $1.29 per share, with pro forma as adjusted net tangible book value of $143.8 million after the offering.

Use of proceeds and capital allocation

  • Net proceeds from the offering will fund ongoing and planned research and development, working capital, and general corporate purposes.

  • Pending use, proceeds will be invested in short- and intermediate-term, interest-bearing obligations, investment-grade instruments, certificates of deposit, or U.S. government obligations.

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Q4 202527 Mar, 2026
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Frequently asked questions

Precision BioSciences Inc. is a U.S.-based biotechnology company focused on developing gene editing technologies. The company utilizes its proprietary ARCUS genome editing platform to research and develop treatments for genetic disorders and cancers. Its work spans cell and gene therapies, with applications in both in vivo and allogeneic CAR T-cell therapies. Precision BioSciences collaborates with academic institutions and pharmaceutical companies to advance its research and clinical programs. The company is headquartered in Durham, North Carolina, and its shares are listed on the NASDAQ.

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