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Maze Therapeutics (MAZE) investor relations material

Maze Therapeutics SEO filing summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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SEO filing summary17 Oct, 2025

Company overview and business model

  • Clinical-stage biopharmaceutical company focused on developing small molecule precision medicines for kidney and metabolic diseases, including obesity, using a proprietary Compass platform for genetic variant functionalization.

  • Lead programs include MZE829, an oral APOL1 inhibitor for APOL1-mediated kidney disease, and MZE782, an oral SLC6A19 inhibitor for phenylketonuria (PKU) and chronic kidney disease (CKD).

  • MZE829 completed Phase 1 with favorable safety and PK results; Phase 2 initiated in November 2024 with proof-of-concept data expected in Q1 2026.

  • MZE782 completed Phase 1 with positive safety and PK data; two Phase 2 trials planned for 2026 in PKU and CKD.

Financial performance and metrics

  • September 2025 private placement raised approximately $150 million in gross proceeds, before fees and expenses.

  • Proceeds intended to fund clinical development, research, and general corporate purposes.

  • As of September 30, 2025, 48,076,885 shares of common stock were outstanding.

Use of proceeds and capital allocation

  • No proceeds from the resale of shares by selling stockholders; company will only receive proceeds from exercise of pre-funded warrants.

  • Private placement proceeds allocated to advancing MZE829 and MZE782, research programs, Compass platform development, and working capital.

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Q3 202512 Nov, 2025
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