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Maze Therapeutics (MAZE) investor relations material
Maze Therapeutics SEO filing summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Company overview and business model
Clinical-stage biopharmaceutical company focused on developing small molecule precision medicines for kidney and metabolic diseases, including obesity, using a proprietary Compass platform for genetic variant functionalization.
Lead programs include MZE829, an oral APOL1 inhibitor for APOL1-mediated kidney disease, and MZE782, an oral SLC6A19 inhibitor for phenylketonuria (PKU) and chronic kidney disease (CKD).
MZE829 completed Phase 1 with favorable safety and PK results; Phase 2 initiated in November 2024 with proof-of-concept data expected in Q1 2026.
MZE782 completed Phase 1 with positive safety and PK data; two Phase 2 trials planned for 2026 in PKU and CKD.
Financial performance and metrics
September 2025 private placement raised approximately $150 million in gross proceeds, before fees and expenses.
Proceeds intended to fund clinical development, research, and general corporate purposes.
As of September 30, 2025, 48,076,885 shares of common stock were outstanding.
Use of proceeds and capital allocation
No proceeds from the resale of shares by selling stockholders; company will only receive proceeds from exercise of pre-funded warrants.
Private placement proceeds allocated to advancing MZE829 and MZE782, research programs, Compass platform development, and working capital.
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