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Jasper Therapeutics (JSPR) investor relations material
Jasper Therapeutics Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Positive clinical data for briquilimab in chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU), and asthma, supporting further development.
CEO transition with Jeet Mahal appointed to lead the next phase of clinical growth.
Internal investigation into anomalous clinical data found no drug product issues and led to process improvements.
Financial highlights
Cash and cash equivalents at year-end 2025 totaled $28.7 million, down from $71.6 million at year-end 2024.
Net loss for Q4 2025 was $9.1 million, and for the full year 2025 was $75.8 million, compared to $71.3 million in 2024.
Research and development expenses for Q4 2025 were $11.4 million; full year R&D was $63.1 million.
General and administrative expenses for Q4 2025 were $4.5 million; full year G&A was $20.8 million.
Net loss per share was $0.32 for Q4 2025 and $3.95 for the year.
Outlook and guidance
Phase 2b/3 study in CSU planned to commence in the second half of 2026, pending capital availability.
Further clinical development in asthma contingent on competitive landscape, partnerships, and funding.
- Briquilimab delivers rapid urticaria control; pivotal trials and equity financing are planned.JSPR
TD Cowen 46th Annual Health Care Conference2 Mar 2026 - Briquilimab delivers rapid, durable efficacy in urticaria and asthma with strong safety and market potential.JSPR
Corporate presentation2 Mar 2026 - Briquilimab targets mast cell depletion in CSU, CIndU, and asthma, with key data expected in 2024.JSPR
Jefferies 2024 Global Healthcare Conference1 Feb 2026 - Key phase II urticaria and asthma study milestones for briquilimab expected in Q4.JSPR
H.C. Wainwright 26th Annual Global Investment Conference 202421 Jan 2026 - Key data from briquilimab trials in CSU and CIndU expected in Q4, with asthma trial also advancing.JSPR
2024 Cantor Fitzgerald Global Healthcare Conference20 Jan 2026 - BEACON study data on briquilimab's efficacy and safety expected in Q4, guiding next trial steps.JSPR
TD Cowen Chronic Urticaria Summit20 Jan 2026 - Briquilimab achieved 93% response and strong safety in CIndU; more data expected in 2025.JSPR
Study Result19 Jan 2026 - Briquilimab shows strong efficacy in urticaria, with pivotal Beacon study results expected soon.JSPR
Stifel 2024 Healthcare Conference13 Jan 2026 - Key CSU trial data in January will highlight efficacy, safety, and dosing advantages.JSPR
7th Annual Evercore ISI HealthCONx Conference12 Jan 2026
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