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Brainstorm Cell Therapeutics (BCLI) investor relations material
Brainstorm Cell Therapeutics Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Advanced NurOwn into a Phase 3b confirmatory study for ALS after FDA clearance in May 2025, aiming for BLA submission if successful.
Secured $2 million in strategic financing post year-end, supporting operational activities and resulting in a significant share re-rating.
Durable long-term survival observed in Expanded Access Program cohort, supporting focus on earlier-stage ALS populations in upcoming trials.
Financial highlights
Cash, cash equivalents, and restricted cash were $0.3 million as of December 31, 2025; $2 million in new funding secured in early 2026.
Research and development expenses for 2025 were $4.2 million, down from $4.7 million in 2024.
General and administrative expenses were $5.8 million in 2025, compared to $7.0 million in 2024.
Net loss for 2025 was $10.3 million, improved from $11.6 million in 2024.
Net loss per share was $1.11 in 2025, compared to $2.31 in 2024.
Outlook and guidance
Phase 3b ENDURANCE trial of NurOwn is set to enroll approximately 200 participants, with a two-part design to assess efficacy and long-term safety.
Strategic financing provides cash runway to execute key operational activities and preparatory work for the planned trial.
- Phase III-B ALS trial advances with FDA alignment, CRO engagement, and new financing secured.BCLI
Status Update3 Feb 2026 - Q2 2024 featured lower net loss, regulatory milestones, and $4M in new funding amid Nasdaq risks.BCLI
Q2 20241 Feb 2026 - NurOwn's new phase III-B trial targets early ALS with promising efficacy and biomarker results.BCLI
Status Update11 Jan 2026 - Phase 3B ALS trial on track for Q1 2025, with strong FDA alignment and funding progress.BCLI
Status Update10 Jan 2026 - Net loss narrowed, funding secured, and pivotal ALS trial preparations advanced amid financial risks.BCLI
Q4 202426 Dec 2025 - Shelf registration for $172.6M in securities; $5.8M at-the-market offering via Raymond James.BCLI
Registration Filing16 Dec 2025 - Up to 16.7M shares registered for resale from warrants, with proceeds supporting operations.BCLI
Registration Filing16 Dec 2025 - Registering 2.76M shares for resale, with proceeds from warrant exercises funding operations.BCLI
Registration Filing16 Dec 2025 - Registering 16.7M shares for resale, with warrant proceeds to fund operations amid Nasdaq risks.BCLI
Registration Filing16 Dec 2025
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