Upstream Bio (UPB) AGM 2026 summary

Opening remarks and agenda

• Meeting called to order by the CEO, with board members, management, and independent auditor present.

• Meeting conducted virtually in accordance with bylaws and Delaware law.

• Rules of conduct and voting eligibility outlined; only stockholders of record as of April 13, 2026, or their proxies, may participate.

Board and executive committee updates

• Two nominees, Edd Fleming and Liam Ratcliffe, were nominated for Class II director positions for three-year terms.

• No stockholder nominations for directors were received in advance.

Shareholder proposals

• Election of two Class II directors and ratification of PricewaterhouseCoopers LLP as independent auditor for fiscal year ending December 31, 2026, were the main proposals.