Senti Biosciences (SNTI) Registration filing summary
Event summary combining transcript, slides, and related documents.
Registration filing summary
18 Jun, 2026Company overview and business model
Clinical-stage biotechnology company developing next-generation cell and gene therapies using proprietary gene circuit platform technologies for incurable diseases.
Focus on engineering CAR-NK cells to target cancer, aiming for high specificity and control over therapeutic effects.
Mission centers on creating smarter medicines that can sense, compute, and respond to complex disease environments.
Financial performance and metrics
As of March 31, 2026, net tangible book value was $(10.0) million, or $(0.32) per share, with 31,144,754 shares outstanding.
After the offering, pro forma net tangible book value would be $(0.6) million, or $(0.01) per share, with immediate dilution of $0.64 per share to new investors.
Company has incurred recurring losses, negative cash flows, and has an accumulated deficit, raising substantial doubt about its ability to continue as a going concern.
Use of proceeds and capital allocation
Will not receive proceeds from the resale of shares by the selling securityholder; received approximately $9.7 million in net proceeds from the issuance of convertible notes.
Latest events from Senti Biosciences
- Q2 net loss narrowed, cash fell, and a merger will leave only early-stage assets and CVRs for shareholders.SNTI
Q2 2026 - Shareholders will vote on a merger offering milestone-based CVRs, not cash, for their shares.SNTI
Proxy filing - Majority of shares registered for resale could shift control and cause significant dilution.SNTI
Registration filing - Shareholders to receive milestone-based CVRs as core assets are spun off in a strategic merger.SNTI
Proxy filing - SENTI-202 demonstrates durable, MRD-negative responses in AML using innovative logic gating technology.SNTI
The Citizens JMP Life Sciences Conference 2025 - Q1 2026 saw SENTI-202 clinical progress, narrowed net loss, and new $40M financing.SNTI
Q1 2026 - SENTI-202 achieved 50% ORR and 42% CR/CRh with excellent safety in R/R AML Phase 1 trial.SNTI
Corporate presentation - Positive SENTI-202 clinical progress, RMAT status, and $61.4M net loss with $16.4M cash.SNTI
Q4 2025 - SENTI-202 achieved 42% CR/CRh in AML with strong safety and rapid recovery, advancing to pivotal trials.SNTI
Leerink Global Healthcare Conference 2026