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Swedish Orphan Biovitrum (SOBI) investor relations material

Swedish Orphan Biovitrum Q3 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2025 earnings summary20 Oct, 2025

Executive summary

  • Achieved 21% revenue growth at constant currency in Q3 2025, driven by a 39% increase in the strategic growth portfolio and strong commercial execution.

  • Adjusted EBITDA/EBITA margin reached 47%, reflecting robust business momentum and disciplined cost control.

  • Upgraded guidance for both sales and EBITDA/EBITA for the full year 2025 due to strong performance and pipeline progress.

  • Significant pipeline milestones, including regulatory progress for NASP, DOPTELET, and Tryngolza (olezarsen), and FDA acceptance of BLA for NASP.

  • Non-cash impairment of Vonjo/Bonjour by SEK 6.6 billion due to competitive pressures and lower-than-expected sales, with future growth initiatives underway.

Financial highlights

  • Q3 total revenue was SEK 7,776 million, up 21% year-over-year at constant currency.

  • Adjusted gross margin was 80% in Q3 2025, with positive mix effects offset by lower Beyfortus royalties.

  • Adjusted EBITDA/EBITA was SEK 3,672–3,700 million (47% margin), up from 43% last year.

  • Adjusted EPS before dilution grew 40% in Q3, excluding impairment and one-off items.

  • Operating cash flow was SEK 1,840 million, up from SEK 1,201 million last year.

Outlook and guidance

  • Upgraded 2025 revenue guidance to low double-digit percentage growth at constant currency.

  • Adjusted EBITDA/EBITA margin guidance raised to mid to high 30s percent of revenue.

  • Continued growth expected in Q4, especially from Altuvoct, DOPTELET, and Gamifant.

  • Operating expenses expected to increase in Q4 due to launch investments and R&D.

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Frequently asked questions

Swedish Orphan Biovitrum AB, an integrated biotechnology company, researches, develops, manufactures, and sells pharmaceuticals in the therapeutic areas of haematology, immunology, and genetic and metabolic diseases in Europe, North America, and internationally. The company operates through three segments: Haemophilia & Hereditary Diseases, Inflammation & Immunology, and Other. It offers Alprolix for hemophilia B; Elocta to treat hemophilia A; Doptelet for thrombocytopenia; Kineret for rheumatoid arthritis; Thiola for cystinuria; Xultophy Cartridge that is used with Flexpen for treatment of diabetes; and Velphoro for hyperphosphatemia.

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