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Edge20 Mar 2026
Tetra Pak: The Shape of Innovation
The story of Tetra Pak, the Rausing family, and how a paper tetrahedron gave rise to a company that now delivers almost 180 billion packages a year.
Sirnaomics
Sirnaomics (2257) investor relations material
Sirnaomics H2 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.H2 2025 earnings summary27 Mar, 2026
Executive summary
Achieved significant clinical milestones in RNAi therapeutics, advancing late-stage programs for oncology, aesthetics, and cardiometabolic diseases.
Completed Phase I trials for STP705 (focal fat reduction) and STP707 (solid tumors), with robust safety and efficacy data.
Advanced GalAhead™ platform, with STP122G in final Phase I cohort and IND-enabling work for STP125G completed.
Implemented comprehensive restructuring, reducing costs and focusing resources on high-potential assets.
Expanded intellectual property portfolio, now holding over 110 patents and applications globally.
Financial highlights
No revenue generated in 2025; 2024 revenue was $1.8 million from licensing.
Loss for 2025 narrowed to $14.6 million from $50.2 million in 2024, driven by lower R&D and administrative expenses.
Administrative expenses fell 71% to $5.0 million; R&D expenses dropped 50% to $10.3 million.
Cash and cash equivalents increased to $13.5 million as of December 31, 2025.
Net cash used in operating activities reduced by 53% to $9.2 million.
Outlook and guidance
Targeting NDA filing for STP705 by 2027, pending regulatory approval and funding.
Preparing IND submissions for GalAhead™ candidates STP125G and STP144G in 2026.
Focused on commercializing STP705 and expanding into new therapeutic areas.
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Latest events from Sirnaomics
- Net loss narrowed to US$50.2M on cost cuts, but a US$18.2M investment loss and audit risks remain.2257
H2 20244 Dec 2025 - Net loss rose to US$43.5 million on investment loss; cash fell to US$7.7 million.2257H1 20244 Dec 2025
- Net loss dropped to US$3.4M on cost cuts; liquidity and financing remain key concerns.2257H1 20254 Dec 2025
Next Sirnaomics earnings date
H1 202628 Aug, 2026
Sirnaomics
Next Sirnaomics earnings date
H1 202628 Aug, 2026
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