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Sanofi (SAN) investor relations material
Sanofi Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
Executive summary
- Q3 2025 sales reached €12.4 billion, up 7% at constant exchange rates, driven by new pharma launches and Dupixent, which exceeded €4 billion in quarterly sales for the first time. 
- New product launches contributed 15% of total sales, with strong uptake for ALTUVIIIO, Ayvakit, and Wayrilz. 
- Vaccine sales declined 7.8% to €3.4 billion due to competitive price pressure and lower flu immunization rates, especially in the U.S. 
- Beyfortus expanded to over 40 countries, while Altuvio is on track for blockbuster status; RSV toddler program discontinued. 
- The company reaffirmed its 2025 guidance for high single-digit sales growth and low double-digit business EPS growth at constant exchange rates. 
Financial highlights
- Net sales: €12,434 million (+7% CER, +2% actual); business EPS: €2.91 (+13.2% CER); gross margin: 78.9% (+2.3pp); business operating income: €4,445 million (+8.5% CER). 
- Free cash flow for Q3 2025 was €2,994 million; YTD free cash flow: €5,452 million (+50.8% vs. prior year). 
- Operating expenses rose 6–7.1%; R&D expenses increased 4.9–5%. 
- Effective tax rate: 19.3% (down 0.7pp year-over-year). 
- Currency headwinds reduced reported growth by 4.7pp in Q3. 
Outlook and guidance
- 2025 guidance reaffirmed: high single-digit sales growth and low double-digit business EPS growth at CER. 
- R&D and sales/marketing investments to continue in 2026, with G&A costs targeted to remain stable. 
- Around €500 million in capital gains from divestments expected in 2025 and 2026. 
- Amvuttra royalties projected at €700 million in 2026; Regeneron R&D reimbursement to decrease by €300 million in 2026 and €800 million in 2027, creating a €500 million EBIT gap in 2027. 
- Anticipated currency impact for full-year 2025: -4% on sales and -6% on business EPS. 
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