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Visual31 Oct 2025
Three decades of Rolls-Royce
Orion (ORNBV) investor relations material
Orion Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary28 Oct, 2025
Executive summary
Nubeqa (darolutamide) received European Commission approval for use with ADT in metastatic hormone-sensitive prostate cancer, driving all-time high royalties and product deliveries to Bayer in Q3 2025.
Generics and Consumer Health segments delivered strong growth, supported by robust product availability and successful new launches.
The ODM-105 insomnia program was discontinued after failing to meet efficacy targets in phase II.
All major business divisions grew, with Nubeqa as the primary growth driver.
The company continues to invest in R&D, focusing on oncology and pain, with plans to advance several clinical programs in 2026.
Financial highlights
Q3 2025 net sales were EUR 423.2 million, down 10.2% year-over-year due to absence of major milestones, but underlying net sales grew 24%.
Q3 2025 operating profit was EUR 121.0 million, down 40.1% year-over-year, but underlying operating profit rose 68%.
For the first nine months, net sales reached EUR 1,194.2 million, up 7.8% year-over-year; underlying net sales up 22%.
Operating profit for the first nine months was EUR 303.5 million, up 22.1% year-over-year; underlying operating profit up 57%.
Q3 2024 included EUR 130 million in milestones, making direct comparison challenging.
Outlook and guidance
2025 net sales guidance set at EUR 1,640–1,720 million; operating profit expected at EUR 410–490 million.
Guidance range narrowed due to increased visibility with only two months left in the year; Nubeqa and R&D costs remain key variables.
Outlook excludes material milestone payments; a potential EUR 180 million Nubeqa milestone could be recorded in 2026 or possibly 2025.
Growth expected in Branded Products (driven by Easyhaler), Animal Health, and Generics and Consumer Health divisions.
R&D costs expected to increase in 2025.
Clarify Nubeqa's EUR 180M milestone payment timing
Future R&D focus after ODM-105 termination
Address Fermion's capacity constraints
Nubeqa Q4 royalty rate expectations?
Impact of ODM-208 endpoint changes?
What are key uncertainties for remaining 2025?
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Frequently asked questions
Orion's Pharmaceuticals business area develops, produces and markets pharmaceuticals for various indications; provides specialized dietary products and enteral feeds for the needs of healthcare, including clinical nutrition services; manufactures APIs; and offers contract manufacturing, research and development (R&D), technical development services in the field of chemistry and biochemistry, as well as develops and commercializes patient monitoring and self-monitoring products. Orion Oyj was founded in 1917 and is headquartered in Espoo, Finland.
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