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Medpace
Medpace (MEDP) investor relations material
Medpace Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q4 2025 earnings summary10 Feb, 2026
Executive summary
Q4 2025 revenue rose 32% year-over-year to $708.5 million; full year revenue was $2.53 billion, up 20%.
Net new business awards in Q4 were $736.6 million, up 39.1%; full year awards totaled $2.65 billion, up 18.7%.
Backlog cancellations reached a multi-year high, leading to a Q4 net book-to-bill ratio of 1.04.
Oncology was the largest therapeutic area in 2025, accounting for 31% of revenue; small biopharma contributed 79%.
The business environment is described as adequate and improving, with strong oncology bookings and elevated metabolic cancellations.
Financial highlights
Q4 2025 EBITDA was $160.2 million (22.6% margin), up 20% year-over-year; full year EBITDA was $557.7 million (22% margin), up 16.1%.
Q4 net income was $135.1 million, up 15.5%; full year net income was $451.1 million, up 11.6%.
Q4 EPS was $4.67 (up from $3.67); full year EPS was $15.28 (up from $12.63).
Free cash flow for Q4 was $188.1 million; year-end cash and equivalents were $669.4 million.
Cash flow from operations in Q4 was $192.7 million; year-end cash balance was $497 million.
Outlook and guidance
2026 revenue expected at $2.755–$2.855 billion, representing 8.9%–12.8% growth.
2026 EBITDA forecasted at $605–$635 million, up 8.5%–13.9%; net income expected at $487–$511 million.
2026 EPS guidance is $16.68–$17.50; assumes 18.5%–19.5% tax rate and no further share repurchases.
Reimbursable costs expected to be 41%–42% of revenue in 2026, with higher levels early in the year.
Headcount growth in 2026 anticipated in the mid to high single digits.
What caused the 2025 margin compression?
What is the plan for remaining share repurchase authorization?
What drives the 2026 revenue growth deceleration?
Q4 cancellation rate vs. historical range?
2026 metabolic trial mix impact on revenue?
Retention's impact on 2026 margin expansion?
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Next Medpace earnings date
Q1 202621 Apr, 2026
Medpace
Next Medpace earnings date
Q1 202621 Apr, 2026
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Frequently asked questions
Medpace Holdings Inc., a full-service clinical research organization, provides clinical research-based drug and medical device development services in North America, Europe, and Asia. It offers therapeutic expertise in the areas of endocrinology, gastroenterology, general medicine, hematology/oncology, infectious diseases/vaccines, and neuroscience.
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