Lytix Biopharma
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Lytix Biopharma (LYTIX) investor relations material

Lytix Biopharma Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary12 Feb, 2026

Executive summary

  • Entered a decisive new phase with strong clinical data, especially for ruxotemitide and LTX-401, and expanded commercialization opportunities.

  • Interim NeoLIPA study in melanoma showed 44% pathological complete response and 55% major pathological response among first 9 patients, shaping future development and regulatory strategy.

  • Partnership with Verrica Pharmaceuticals advanced, with promising immune-response data in basal cell carcinoma and preparations for pivotal Phase III trial.

  • NOK 77.3 million raised in January 2026 via private placement and subsequent offering, strengthening the balance sheet for key milestones.

  • Leadership and board enhanced to support late-stage execution and commercial readiness.

Financial highlights

  • Q4 2025 operating expenses were NOK 21.2 million, down from NOK 33 million year-over-year, mainly due to reduced R&D activity.

  • Cash and short-term investments at Q4 2025 end were NOK 72 million, with NOK 77.3 million raised post-quarter.

  • Total liabilities at Q4 2025 were NOK 20 million, down from NOK 39 million year-over-year.

  • Loss for Q4 2025 was NOK 18.7 million, improved from NOK 31.9 million in Q4 2024.

  • Cash flow from operations was negative NOK 29.5 million in H2 2025, an improvement from negative NOK 33.1 million in H2 2024.

Outlook and guidance

  • Well-capitalized into mid-2027, supporting clinical and partnering milestones, with focus on pivotal studies and commercialization.

  • NeoLIPA topline results expected in H2 2026; pivotal study for ruxotemitide in preparation.

  • LTX-401 clinical entry targeted for 2027, with ongoing evaluation of strategic development opportunities.

  • Actively pursuing capital raising and pharma partnerships to fund pivotal studies.

  • Expectation of continued disciplined execution, targeted investment, and strategic collaboration.

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Frequently asked questions

Lytix Biopharma is a clinical-stage biotechnology company focused on developing cancer immunotherapies. The company specializes in using oncolytic peptides, which are designed to kill cancer cells and stimulate the immune system to generate a strong, systemic T-cell response. This approach aims to overcome the challenges of tumor heterogeneity, where variations in cancer cells within a tumor reduce the effectiveness of conventional immunotherapies. The company is headquartered in Oslo, Norway, and its shares are listed on the Oslo Stock Exchange.

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