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Cadrenal Therapeutics (CVKD) investor relations material
Cadrenal Therapeutics Q4 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Reported encouraging Phase 2 results for CAD-1005 in HIT, showing a significant reduction in thrombotic events versus placebo on top of standard anticoagulant therapy.
Completed End-of-Phase 2 FDA meeting, clarifying the regulatory path for a planned Phase 3 pivotal trial of CAD-1005.
CAD-1005 remains the near-term development priority, with broader 12-LOX platform opportunities under evaluation.
Financial highlights
Research and development expenses for Q4 2025 were $0.7 million, down from $1.5 million in Q4 2024.
General and administrative expenses for Q4 2025 were $2.4 million, compared to $2.7 million in Q4 2024.
Net loss for Q4 2025 was $3.0 million, improved from $4.2 million in Q4 2024.
Cash and cash equivalents as of December 31, 2025, totaled $4.0 million.
Outlook and guidance
Incorporating FDA feedback into the Phase 3 protocol for CAD-1005 is underway.
Evaluating financing and strategic alternatives to support planned clinical development activities.
Continuing to assess longer-term opportunities for the 12-LOX platform in indications beyond HIT.
- CAD-1005 moves to phase III for HIT, aiming to address a critical unmet need with strong safety data.CVKD
Life Sciences Virtual Investor Forum12 Mar 2026 - Tecarfarin targets unmet anticoagulation needs in LVAD patients, with pivotal trials and partnerships ahead.CVKD
Sidoti Micro-Cap Virtual Conference2 Feb 2026 - Tecarfen aims to replace warfarin for high-risk heart patients, nearing FDA review with strong data.CVKD
Summer 2024 Investor Summit Virtual MicroCap Forum23 Jan 2026 - Tecarfarin aims to displace warfarin, with pivotal LVAD studies and strong regulatory momentum.CVKD
Lytham Partners Fall 2024 Investor Conference19 Jan 2026 - VLX-1005 and Tecarfarin lead a strategy to address unmet needs in rare anticoagulation markets.CVKD
2nd Annual Lytham Partners Healthcare Investor Summit15 Jan 2026 - VLX-1005 leads a pipeline targeting critical gaps in anticoagulation for rare, high-risk patients.CVKD
Investor presentation15 Jan 2026 - Tecarfarin targets gaps in anticoagulation for rare heart conditions; a pivotal trial is planned for 2025.CVKD
Lytham Partners 2025 Investor Healthcare Summit10 Jan 2026 - Registers 428,227 shares for resale from warrant exercises, with proceeds for working capital.CVKD
Registration Filing29 Dec 2025 - Registering 590,001 shares for resale, proceeds from warrant exercises will fund Phase 3 trial.CVKD
Registration Filing16 Dec 2025
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Next Cadrenal Therapeutics earnings date
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