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Alterity Therapeutics (ATH) investor relations material
Alterity Therapeutics Q1 2026 TU earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q1 2026 TU earnings summary31 Oct, 2025
Executive summary
Positive clinical results for ATH434 in both double-blind and open-label Phase 2 trials for Multiple System Atrophy (MSA), with efficacy signals at high dose levels and similar treatment effects in advanced and earlier-stage patients.
Independent commercial assessment estimates a USD $2.4 billion worldwide peak sales opportunity for ATH434 in MSA, reflecting strong physician interest and market potential.
Active engagement with the FDA, leveraging Fast Track Designation, to align on nonclinical, CMC, and clinical development requirements for Phase 3 initiation, with key meetings scheduled through mid-2026.
Financial highlights
Cash balance as of 30 September 2025 was A$54.56M, up from A$40.66M at the start of the quarter.
Operating cash outflows for the quarter totaled A$5.34M, primarily driven by R&D, staff, and administrative costs.
Gross proceeds of A$20M were raised via a strategic placement to healthcare-focused funds, strengthening the balance sheet.
Outlook and guidance
Series of regulatory meetings with the FDA are planned, culminating in an End-of-Phase 2 meeting in mid-2026 to finalize Phase 3 trial design and requirements.
Estimated funding runway of 10.2 quarters based on current cash position and operating outflows.
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Frequently asked questions
Alterity Therapeutics Limited is a biotechnology company focused on developing therapies for neurodegenerative diseases. The company specializes in small molecule treatments designed to target underlying biological processes associated with disorders such as Parkinsons and other neurological conditions. The company is headquartered in Melbourne, Australia, and its shares are listed on the ASX.
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